Collagen Is Key

A SOURCE OF SMOOTH SKIN

Collagen is a fibrous protein in the deep dermis that gives skin structure and supports the functions of elastin and hyaluronic acid (HA), which helps maintain the skin's shape, while keeping it smooth and hydrated. A healthy supply of collagen makes for a more youthful-looking complexion.1-7

How Much Collagen Have You Lost?
You lose about 1% of collagen per year8
Please enter an age between 18 and 90
0%

For estimation purposes only. Percentages reflect the relationship of skin collagen content (expressed per unit
of skin surface area) to age in 74 males and 80 females ages 15–93 who participated in a clinical study.8

Sculptra® uses poly-L-lactic acid to help rebuild collagen for a more youthful-looking appearance that can last up to two years*
Sculptra® poly-L-lactic acid
*Individual results and treatment regimens may vary. Clinical trial ended at 96 weeks (2 years).
sculptra collagen patient at beach

-25% By 45, you face up to 25% collagen loss.8

A Conversation on Aging

Hear Kate and her friends discuss their changing perspectives on aging, beauty and what they want out of treatment.

Other Facial Aging Treatments
1
Resurfacing

Chemical peels, microdermabrasion and laser resurfacing modify the surface of the skin to correct visible signs of sun damage, such as fine lines, irregular pigmentation and blemishes.9

2
Injectables

Toxins, traditional fillers (hyaluronic acid) and collagen stimulators are injected into facial areas to reduce the appearance of lines and wrinkles and restore facial contours.10,11

3
Surgery

A wide range of surgical procedures exist, like liposuction, face-lifts and fat transfers, which are used to remove excess fat, lift severely sagging skin or fill facial hollows. These are the most invasive types of treatment.12-14

  • Sculptra Logo White

  • NOW FDA-APPROVED FOR

    CHEEK WRINKLES

  • The first and original PLLA collagen stimulator that, when injected in the cheek area, has been clinically shown to reduce cheek wrinkles, firm the skin and improve skin quality.1-4
    1. Sculptra. Instructions for Use. Galderma Laboratories, L.P. 2023.
    2. Data on file. 43USSA1812EXT clinical study report. Fort Worth, TX: Galderma Laboratories, L.P. 2022.
    3. Bohnert K. et al. Randomized, Controlled, Multicentered, Double-Blind Investigation of Injectable Poly-L-Lactic Acid for Improving Skin Quality Dermatol Surg2019;45:718–724.
    4. Bergeret-Galley C. Comparison of Resorbable Soft Tissue Fillers. Aesthetic Surg J 2004; 24:33-46.

References:
  1. Deshmukh SN, Dive AM, Moharil R, Munde P. Enigmatic insight into collagen. J Oral Maxillofac Pathol. 2016;20(2):276–283. doi:10.4103/0973-029X.185932
  2. Skin. Cleveland Clinic website. https://my.clevelandclinic.org/health/articles/10978-skin. Accessed December 3, 2019.
  3. Vollmer DL, West VA, Lephart ED. Enhancing Skin Health: By Oral Administration of Natural Compounds and Minerals with Implications to the Dermal Microbiome. Int J Mol Sci. 2018;19(10):3059. Published 2018 Oct 7.
  4. Aging and skin care. Cleveland Clinic website. https://my.clevelandclinic.org/health/articles/10979-aging-and-skin-care. Accessed December 3, 2019.
  5. Papakonstantinou E, Roth M, Karakiulakis G. Hyaluronic acid: A key molecule in skin aging. Dermatoendocrinol. 2012;4(3):253–258. doi:10.4161/derm.21923
  6. Avila Rodríguez MI, Rodríguez Barroso LG, Sánchez ML. Collagen: A review on its sources and potential cosmetic applications. J Cosmet Dermatol. 2018 Feb;17(1):20-26.
  7. Borumand M, Sibilla S. Daily consumption of the collagen supplement Pure Gold Collagen® reduces visible signs of aging. Clin Interv Aging. 2014;9:1747–1758. Published 2014 Oct 13.
  8. Shuster S, Black MM, McVitie E. The influence of age and sex on skin thickness, skin collagen and density. Br J Dermatol. 1975;93:639-643.
  9. Skin resurfacing guide. American Board of Cosmetic Surgery website. https://www.americanboardcosmeticsurgery.org/procedure-learning-center/non-surgical/skin-resurfacing-guide/. Accessed December 3, 2019.
  10. Botox-type injectables guide. American Board of Cosmetic Surgery website. https://www.americanboardcosmeticsurgery.org/procedure-learning-center/non-surgical/guide-botox-type-injectables/. Accessed December 3, 2019.
  11. Facial fillers for wrinkles. Mayo Clinic website. https://www.mayoclinic.org/tests-procedures/facial-fillers/about/pac-20394072. Accessed December 3, 2019.
  12. Liposuction for sagging skin. American Society for Dermatologic Surgery. https://www.asds.net/skin-experts/skin-treatments/liposuction/liposuction-for-sagging-skin. Accessed December 3, 2019.
  13. Face-lift. Mayo Clinic website. https://www.mayoclinic.org/tests-procedures/face-lift/about/pac-20394059. Accessed December 3, 2019.
  14. Fat transfers for wrinkles. American Society for Dermatologic Surgery. https://www.asds.net/skin-experts/skin-treatments/fat-transfers-for-wrinkles. Accessed December 3, 2019.

Patient Brochure

Click here for patient information about Sculptra® (PDF)

Important Safety Information

Indication: Sculptra® (injectable poly-L-lactic acid (PLLA-SCA)) is indicated for use in people with healthy immune systems for the correction of shallow to deep nasolabial fold contour deficiencies, fine lines and wrinkles in the cheek region, and other facial wrinkles.

Sculptra should not be used by people that are allergic to any ingredient of the product or have a history of keloid formation or hypertrophic scarring. Safety has not been established in patients who are pregnant, lactating, breastfeeding, or under 18 years of age.

Sculptra has unique injection requirements and should only be used by a trained healthcare practitioner. Contour deficiencies should not be overcorrected because they are expected to gradually improve after treatment.

Sculptra should not be injected into the blood vessels as it may cause vascular occlusion, infarction or embolic phenomena. Use at the site of skin sores, cysts, pimples, rashes, hives or infection should be postponed until healing is complete. Sculptra should not be injected into the red area (vermillion) of the lip or in the peri-orbital area.

The most common side effects after initial treatment include injection site swelling, tenderness, redness, pain, bruising, bleeding, itching and lumps. Other side effects may include small lumps under the skin that are sometimes noticeable when pressing on the treated area. Larger lumps, some with delayed onset with or without inflammation or skin discoloration, have also been reported.

Sculptra is available only through a licensed practitioner. View the complete Instructions for Use.

Important Safety Information | Instructions for Use

Indication: Sculptra® (injectable poly-L-lactic acid (PLLA-SCA)) is indicated for use in people with healthy immune systems for the correction of shallow to deep nasolabial fold contour deficiencies, fine lines and wrinkles in the cheek region, and other facial wrinkles.

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